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The global burden of dementia is staggering—it is a trillion dollar problem—and it is growing. Of the currently living Americans, about 45 million will die with Alzheimer’s disease (about 15% of the population). 75 million have the important genetic risk factor, ApoE4. Cognitive decline associated with Alzheimer’s disease and its precursors (MCI and SCI) can be prevented and reversed. The optimal approach for complex chronic illnesses such as Alzheimer’s disease is not a mono therapy but a personalized program that addresses all of the contributors. The many cases of Alzheimer’s diseas
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