Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens permanently off the conventional course.
Like the ten Biblical plagues, they are hit by one catastrophe after another; violence, evictions, arrests, a suicide attempt, a near-drowning, even cancer and a brain tumor play against the backdrop of a wild teenage bacchanal of artmaking and drugs. With no time for hand-wringing, Miriam advances, convinced she can fix everything. This is the story of how