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BEING Outside the Box

BEING Outside the Box

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January 29th 2013:Low Intensity Vibrational Therapy as a Non-Drug Treatment

Exercise is perhaps the single “intervention” recognized as a deterrent to systemic diseases such as osteoporosis, sarcopenia, diabetes and obesity, yet the manner in which mechanical signals inhibit their pathogenesis remains unknown. In an effort to understand what aspects of exercise are critical to the achievement and retention of musculoskeletal wellness, our work has led us to focus on how brief daily periods of high frequency-low intensity vibration (LIV) is anabolic to both bone and muscle. These signals serve as a surrogate for the spectrum of low-level mechanical signals provided b

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Clinton Rubin, Ph.D.

Clinton Rubin, Ph.D., is a SUNY Distinguished Professor and Chair of the Department of Biomedical Engineering at the State University of New York, in Stony Brook, NY. His work is targeted towards understanding the cellular mechanisms responsible for the growth, healing, and homeostasis of bone, and how mechanical stimuli mediate these responses through the control of mesenchymal stem cell differentiation and proliferation. The clinical significance of this work is applicable to the inhibition of osteopenia and sarcopenia, the promotion of bony ingrowth, the acceleration of fracture healing, with studies that indicate that low-level mechanical signals can reverse osteoporosis in children wit
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